







Bio360AI is a comprehensive Health Digital Twin architecture that unifies longitudinal multi-modal datasets with predictive computational engines.
Multimodal Cohort & Domain Integration
Predictive Modeling & Clinical Impact
Integrates wearable, laboratory, lifestyle, family-history, and clinical data across MIMIC-IV cohorts to evaluate six physiological domains: cardiovascular, respiratory, metabolic, strength and functional health, lifestyle balance, and cognitive wellness.
Generates personalized health scores, risk factors, lifestyle simulations, treatment-response comparisons, and physiological projections at 5, 10, 15, and 20 years. Supported by two IEEE publications, workshop/poster presentations, a mobile app, and 100+ waitlist sign-ups.
Bio360AI Health Digital Twin


Featured Research Projects
UMD School of Medicine
UMBC RISE Lab
Sun2Water Purification
Analysis of tacrolimus, prednisone, mycophenolate mofetil, fingolimod, and rapamycin at Days 3, 7, and 30 using microbiome, metabolomic, transcriptomic, and immune data via PCA, SparCC, heatmaps, mixOmics, longitudinal comparisons, and untreated controls.
Contribution to LLM workflows that detect software vulnerabilities, identify root causes, generate targeted code fixes, and rigorously evaluate whether automated fixes resolve defect patterns.
Solar-powered purification system using multi-stage filtration, UV disinfection, water-quality monitoring, and automated dispensing producing 300 to 800 L/day. Recognized in National Top 50 from 1,200+ submissions with $2,000+ funding.
BrainBoost Alzheimer's Study
Early Sepsis and AKI Modeling
A 30-day study with 20+ participants living with Alzheimer’s disease using Muse EEG to monitor alpha and theta brainwave activity alongside cognitive testing, exercise comparisons, and individualized reports.
Analysis of respiratory-rate increases, tachycardia, mean arterial pressure drift, narrowing pulse pressure, oxygen saturation, and delayed creatinine changes using PhysioNet and MIMIC-IV datasets.
IEEE Publications
Bio360: A Multimodal Framework for Health Digital Twin Modeling and Early Physiological Drift Detection
Bio360: From Multimodal Data to Next-Generation Health Analytics
Presents computational methodologies for continuous multimodal integration, evaluating subtle multi-system drift signals to predict health trajectories early.
Details the data pipeline, clinical feature extraction, and analytical algorithms transforming physiological streams into actionable health risk projections.
Selected as an IEEE ICHI 2026 presenter. Featured workshop speaker and poster presenter for Bio360AI health digital twin modeling across regional and national conferences.
Multi-omics analytics (PCA, SparCC, mixOmics, heatmaps), EHR cohort modeling (MIMIC-IV, PhysioNet), Muse EEG analysis, LLM defect detection workflows, and sustainable UV engineering.
